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In: What is it?

For our Fact Friday, we are answering more of your questions!



Q. How does my energy depend on NADH? 
A. The billions of cells that form tissue and organs and ultimately the human body have an 
important assignment: to produce energy. If our cells slow down or decline in their energy 
production, the most visible result is that we are tired and can increasingly experience greater 
overall fatigue. NADH is part of every living cell. Inside each cell a process known as the Krebs cycle combines NADH with Hydrogen to form ATP, your body’s own energy. 

Q. How does the body produce energy? 
A. Bringing hydrogen and oxygen together is one of the most efficient ways to produce energy. A rocket launched into outer space is an example of energy production. All cells in our bodies use the same principle of energy production, but they do so in a sophisticated way to conserve the energy produced. NADH is the biological form of hydrogen that reacts with the oxygen we breathe in to form energy and water. The energy‐ producing process in cells is achieved by a cascade of reactions, which lead to the formation of adenosine triphosphate (ATP), the energy‐containing compound in cells. One molecule of NADH will form three times the amount of ATP. Therefore, NADH is an extremely efficient and effective energy producer. 

Q. How does the body store energy?  
A. Living cells have the capability to store energy in the form of chemical compounds. When these compounds are metabolized, energy is released and used for all cellular processes. Only a few biological substances display all the features of energy‐rich compounds. The most important of these are adenosine triphosphate (ATP), creatine phosphate (CP), nicotinamide adenine dinucleotide hydride (NADH), and nicotinamide adenine dinucleotide phosphate hydride (NADPH). 

Q. How does NADH help my body? 
A. NADH has energy stored in its chemical structure. When it is absorbed and taken up by the body cells, NADH produces energy. NADH can be compared to a turbine in an electric power plant. Water at a higher level has more energy than water at a lower level. If you insert a turbine (wheel) in this waterfall, you can produce electrical energy. Hence, the more NADH a cell has available, the more energy can be produced. The amount of NADH a cell contains depends on the amount of energy the cell requires. Heart muscle cells have the highest NADH content because the heart is the organ that needs the most energy in the body. Cells in the brain and muscles contain 60 percent of the NADH content of those in the heart 

Q. Does NADH enhance the immune system?  
A. Yes, it does. NADH is directly involved in the cellular immune defense system. Special white 
blood cells, called macrophages, are responsible for direct elimination of foreign bodies such as bacteria, viruses, and molds. They literally capture these foreign bodies and then degrade and eliminate them. During this process, a markedly increased metabolic activity including oxygen consumption takes place. Most of the oxygen is converted to superoxide and hydrogen peroxide, which are able to destroy viruses or bacteria. This phenomenon is known as “metabolic burst” and appears to be the first and most critical step leading to the destruction of the foreign invader. Large amounts of NADH are required for this process. Hence, the more NADH your body has available, the more protection your immune system can provide.

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March 28, 2014

Fun Fact Friday! Q&A



We get a lot of questions about our products, so here is a quick Q & A session to answer our most asked questions about NADH products.

Q. Are there any side effects from NADH?

Since the introduction of NADH in the early 1990s, the safety of NADH continues to be supported by several types of clinical data. First, the PDA approved two human clinical trials and any side effects found in these trials were required to be fully documented. The results of these trials were that not a single side effect was reported. In addition, more than three thousand patients have received stabilized NADH for treatment of therapeutic conditions since the late 1980s. No side effects have been observed in these patients. It’s also important to know that hundreds of thousands of consumers have taken NADH since it was made available in health food stores and pharmacies in the United States more than four years ago, and consumers have reported no significant side effects.

Q. Can I take NADH with medication?

Yes, you can take NADH with medication, including the most common antihypertensive, antidepressant, and antihistaminic drugs. In one of the PDA‐approved clinical trials, many patients were on antihypertensive and/or anti‐depressive and/or antihistaminic drugs. No interference was observed with these medications. However, be sure to check with your health care professional for his or her advice.

Q. When is the best time to take NADH?

The best time to take NADH is first thing in the morning on an empty stomach, 30 minutes before any food, drugs, or other supplements, with a glass of water. The NADH tablets are enteric coated and are designed to bypass the stomach and “float” with water into the intestine where absorption takes place. If you need additional energy for the late afternoon or evening, you can also take an additional NADH tablet either thirty minutes before lunch or about two hours after lunch, and again, at least thirty minutes before a late afternoon snack or an early dinner. It is important that NADH is taken on an empty stomach so it can easily “flush” or move into the intestines where it is absorbed.

However, the ENADA MOJO and MOJO Plus tablets can be taken any time, regardless of when you last ate.

Q. How soon should I expect to see results with NADH?

The answer to this question varies according to the individual. Each of us has a very unique biochemistry: Our bodies absorb food and nutrients differently, and our metabolisms often differ in other dramatic ways. On average, optimal effectiveness is shown in four weeks of continuous usage. However, many healthy individuals report an improvement in energy levels within five to ten days. NADH must enter the billions of cell structures for energy production to begin, so first‐time users may need to be patient before seeing beneficial results.

Q. How long can I take NADH?

For normal healthy people who are taking NADH for increased daily energy and mental clarity, optimal effectiveness is achieved within one month of continuous usage. One month, therefore, is the minimum time period to take the product. After one month of continuous usage, normal healthy individuals who supplement with NADH for energy can try using it on an every‐other‐day basis.

However, it is best to take NADH daily. Research suggests that NADH can be taken safely for long periods of time. Many people have been taking NADH for several years with no side effects reported. The body is in a continuous state of refueling itself with cellular energy and NADH is a very efficient cellular energizer. So, the more NADH

the body has available, the more the body will use to produce more energy. If you are taking NADH therapeutically, continuous daily usage is recommended. However, it is always best to check with your healthcare provider to help monitor long‐term usage of any supplement.


We will be doing more Q&A post in the future. If you have any questions make sure to comment or submit one here!

Looking for natural supplements and other alternatives to help you keep a healthy balance in your life? Check out our supplements and their benefits here!