November 15, 2010
Investigators Discover Potential Indicator for Chronic Fatigue Syndrome
CHICAGO, Ill. – The discovery of a potential indicator for chronic fatigue syndrome is among new findings presented at the American College of Allergy, Asthma and Immunology’s (ACAAI) Annual Meeting in Chicago.
Chronic fatigue syndrome (CFS) is a debilitating disorder that causes unexplainable tiredness or lack of energy. It affect s more than 14 million Americans, occurring mainly in adults aged 20 to 40 years and in twice as many women as men.
“Currently, the diagnosis of CFS involves a lengthy procedure of eliminating other possible causes of severe fatigue lasting more than six consecutive months,” said ACAAI Past President Joseph A. Bellanti, M.D., of Georgetown University Medical Center in Washington, D.C. “Hopefully this data will provide a predictive marker of CFS which will help unravel the diagnosis and treatment of this perplexing disorder.”
Investigators used data from a double blind placebo controlled study published February 1999, in the ACAAI’s scientific journal, “Annals of Allergy, Asthma and Immunology.” The study reported subjects taking a nutritional supplement ENADA® – a stabilized oral absorbable form of nicotinamide adenine dinucleotide (NADH) – were four times more likely to show an improvement in CFS symptoms than those taking a placebo.
According to Dr. Bellanti, the follow-up study testing urinary concentrations in 20 of the CFS patients found that 75 percent showed elevated levels of a major breakdown product of serotonin, known as 5-HIAA. When treated with NADH, 70 percent of the patients returned to normal range, whereas in the placebo subjects, 70 percent retained elevated or increasing levels.
“The results of this study suggest that the measurement of urinary 5-HIAA may not only serve as a useful predictive marker of disease activity in CFS patients, but also may provide an objective measure of improvement following therapy with NADH,” said Dr. Bellanti.
The Centers for Disease Control and Prevention (CDC) defined criteria for the diagnosis of chronic fatigue syndrome. Unexplained, debilitating fatigue of at least six month duration must be present, along with four or more of the following symptoms: neurocognitive dysfunction, muscle pain, sore throats, headaches, feeling of being sick or of physical discomfort after exertion, joint pain, sleep disturbances, or swelling and tenderness of lymph nodes.
For assistance in locating an allergist-immunologist, call the ACAAI toll-free number (800) 8427777 or visit its public web site at http://allergy.mcg.edu.
The ACAAI is a professional medical organization comprised of 4,100 qualified allergistsimmunologists and related health care professionals. The College is dedicated to the clinical practice of allergy, asthma and immunology through education and research to promote the highest quality of patient care.
Full-text articles published in “Annals of Allergy, Asthma & Immunology” are available free to media on the Internet at www.annallergy.org through December 2000. Thereafter, access will be limited to subscriptions.
November 13, 2010
A recent clinical study reports that ENADA, a dietary supplement, provides relief for Chronic Fatigue Syndrome (CFS). ENADA, is the only patented, stabilized absorbable, oral form of NADH available. NADH is a naturally occurring coenzyme involved with the body’s energy producing cycle. The more NADH a cell has the more energy it can produce. ENADA is one of the first nutritional supplements to be tested using strict FDA guidelines to determine its safety and effectiveness.
Below is an article, which appeared in the Washington NY times Syndicate on February 24, 1999, pertaining to the CFS study findings:
“Supplement May Energize Some Chronic-fatigue Patients” – A dietary supplement may benefit victims of chronic fatigue syndrome, researchers announced at a news conference here Tuesday. “We’ve demonstrated a real benefit with NADH in this study”, said Dr. Joseph A. Bellanti of the Georgetown University School of Medicine, who led the study of chronic fatigue patients. NADH is a compound found naturally in food that plays a central role in the process by which cells convert food into energy. A poorly understood ailment, CFS symptoms afflict some 500,000 people nationwide, according to Centers for Disease Control and Prevention in Atlanta. Doctors can only diagnose the disease by these symptoms, which includes headaches, body aches, poor concentration, sore throats and lethargy lasting at least six months. Bellanti and his colleagues described the results of a three-month trial of NADH. Of 26 patients given the supplement, eight reported significant lessening of their symptoms, compared with only two of 28 control patients who were taking a placebo. Furthermore, 72 percent of patients in a follow-up study reported that their symptoms improved.
Bellanti and his colleagues theorize that CFS is nothing more than al lack of the chemical adenosine triphosphate (ATP), which provides power to the body. Chronic infections, stress, and other ailments tend to deplete the chemical, according to the researchers. NADH, short for nicotinamide adenine dinucleotide, is the chemical that jumpstarted the production of ATP in muscles, so the researchers hypothesized that simply providing supplements of the chemical might people with chronic fatigue. Patients in the study received 10 milligrams of NADH a day. “They may have stumbled onto something useful”, said Ronald Glazer, a virologist and immunologist at Ohio State University School of Medicine. He argued that so little is currently available to treat the syndrome that CFS patients should consider taking the supplement now.
Healthy individuals desiring more natural energy also benefit from taking ENADA – Over two thirds of the people take ENADA for overall energy enhancement as well as mental clarity. ENADA has been sold in the U.S. since 1995 and tens of thousands of customers are taking ENADA for increased energy. Consumer research indicated that 76% of consumers taking ENADA report improvement in their energy levels. For more information on ENADA and the CFS Georgetown study visit their website at www.enada.com
October 14, 2010
ENADA is the only brand of NADH currently available that is stabilized and is actually protected by several worldwide patents. Competitors continue to try to bypass these patents and introduce NADH products. However, all these products are non-stabilized forms of NADH. When subjected to independent laboratory analysis and validation, the majority of these products do not contain any NADH. The result of the absence of NADH in these products hurts consumers and leaves the impression that NADH is ineffective. Remember, if an NADH product isn’t stabilized, you’re wasting your money.
ENADA has two main types of supplements available. The first is ENADA Vitality and Vitality Plus. This was the first pill we introduced, and is most effective when taken on an empty stomach. That is, first thing in the morning, or at least an hour before eating and/or two hours after eating. This is because of their coating, allowing it to move smoothly into the intestine where it is absorbed. These supplements come in 5mg doses. This is the supplement for users who like to take NADH once or twice daily for their health ailments, rather than for energy boosts.
If you need fast quick-acting energy, we have recently added another supplement to our collection. ENADA MOJO is fast-acting and designed for demanding and active lifestyles. It has been carefully crafted without the enteric coating of the other ENADA pill, thus can be taken at any time, regardless of when you last ate. Also ENADA MOJO comes in 10mg and 20mg doses, so you can tackle that last mile or extra work hours with energy and integrity.
Q. How do I know which is the right NADH supplement for me?
A. It depends on what results you are looking for. If you have an active, busy lifestyle and require more energy in less time, then the MOJO tablets are most likely best for you. The 10mg tablets (ENADA MOJO) are for people who desire quick energy, but aren’t doing anything extreme, such as intense physical exertion. These are best for the everyday person with everyday tasks at hand. The 20mg tablets (ENADA MOJO Plus) are for those that exert a lot of physical effort or are in need of constant energy throughout the day. This may be a triathlete before and during his or her race, or an executive with days constantly full of meetings and negotiations. Simply put, the 20mg is just a more intense than the 10mg, so based on the amount of energy you need, you can decide which supplement is right for you.
If you are taking ENADA supplements for health purposes, the ENADA Vitality (5mg tablets) are for you. These ones are taken daily, in the morning, and have a slower effect as they are dissolved in the lower intestine.
Energy Pills, NADH Supplements, Anti-Fatigue Vitamin
September 16, 2010
Having energy is one of the key elements of being an athlete. Athletes are usually the ones who are most depleted of energy because of how much they exert. Wouldn’t it be amazing if there was a simple, natural way to restore your body’s energy and feel great while doing whatever it is you love to do? There is, with NADH.
NADH is the abbreviation for the naturally occurring biological substance, nicotinamide adenine dinucleotide hydride. It’s biologically ranked coenzyme 1, and plays a vital role in energy production in the mitochondria, where it jumpstarts the production of ATP (cellular energy) in muscles. Therefore the more NADH a cell has, the more energy it can produce. While it has been known about for decades, only recently have scientists been able to put it in a stable form and thus able to be ingested as a pill. ENADA’s product is an energy booster, an immunity booster, and a powerful antioxidant. Because of its crucial role in energy production, it is the perfect supplement for athletes.
Athletes exert more energy than a sedentary person, and thus are often NADH depleted. Therefore a supplement of NADH will boost energy and improve all-around performance of physical activity. Research conducted by Birkmayer and colleagues on competitive athletes indicate that NADH enhances work capacity. Researchers measured reaction times, physical performance, and performance quality in seventeen competitive cyclists and long-distance runners. All subjects took 5 mg of NADH in the mornings on an empty stomach daily for four weeks. The level and amount of exercise each individual underwent remained the same as before they began taking the supplements, to ensure accuracy. After the four weeks, nearly all of the athletes experienced significantly less scattering of reaction times and increases in oxygen capacity. Overall 16 of the 17 subjects had improvements in their reaction times.
Here are some other ways that NADH is the perfect supplement for athletes:
- Increased energy
- Increased reaction time
- Greater mental acuity and alertness
- Improved oxygen capacity
- Immune system boost
Julia Kaplan, an avid cyclist ENADA user, shared her experience with NADH.
The first thing I noticed after getting introduced to NADH was an increase in energy and focus during my training rides. I then started to see improvements in performance. Some of this improvement was due to being able to train longer and recover faster in between hard workouts, or after races.
I used it to prepare for a national record attempt at altitude (6200 feet, I live at sea level) over ten years ago and discovered a benefit I did not expect. My previous experience of racing at altitude was that I would get back home and one or two days later be just hammered. I did not have that huge crash despite doing back to back attempts in a 24 hour period. I was fatigued, yes, nothing like previous years.
But no matter what type of athlete you are, or how strenuously you exert yourself, NADH can help you. All athletes can customize the amount of NADH they take daily by tailoring dosage levels to suit their overall health or training needs.
September 16, 2010
It seems that there is some type of new wonder drug gaining popularity every week, claiming to fix any problem you’ve got. Coenzyme Q10, also known as CoQ10, is one of the recent contenders. But while the benefits of the supplement are advertised as a strong antioxidant, the knowledge that CoQ10 needs NADH in order for the body to experience these benefits is usually omitted.
NADH is the body’s most powerful antioxidant. Nicotinamide adenine dinucleotide hydride is biologically ranked coenzyme 1, the highest level of coenzyme in the body. This means that it is the coenzyme, or cofactor, needed for numerous other enzymes that are involved in cellular energy production. It is also essential for cellular development and acts as an antioxidant. Scientists have acknowledged that it is the body’s most important antioxidant to protect cells from damage caused by harmful substances. ENADA is the stable form of NADH that can be taken as a supplement for the benefit of users suffering from a multitude of diseases, including Alzheimer’s, Parkinson’s disease, chronic fatigue syndrome (CFS), and diabetes. However users who are perfectly healthy benefit from NADH’s effects, such as increased energy, increased libido, weight loss, and immunity boost. Aside from having tons of health benefits of its own, it also works to regenerate other important antioxidants, such as glutathione, vitamin C, and CoQ10.
One of the coenzymes that need NADH for energy production is Coenzyme Q10. CoQ10 is frequently thought to be an antioxidant. Commercially available products boast the positive effects it has on the body when ingested, most frequently increased energy and enhancing the immune system. It’s a coenzyme that naturally occurs in the body, producing energy in the mitochondria in the form of adenosine triphosphate (ATP). It is known to have many other benefits to the body and supplements are taken to cure migraines, heart failure, gum disease, Parkinson’s disease, high blood pressure, and diabetes, among other ailments. However, when Co Q10 is ingested as a supplement, it is in its oxidized form. Therefore, it is not an antioxidant, and completely useless to the body. Only when it is in an antioxidant form do the health benefits exist.
Only when CoQ10 is combined with NADH does it become effective and beneficial to the body. NADH modifies the Co Q10, biologically ranked coenzyme 10, in the body, reducing it into an antioxidant and also an energy-producing compound. So before you run out and purchase a bottle of Coenzyme 10 supplements, remember that you’re wasting your money if you aren’t taking it simultaneously with NADH.